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Shoulder pain traces back to a short list of causes: rotator cuff tears and tendinopathy, subacromial bursitis and impingement, a frozen shoulder, a SLAP or labral tear, instability after dislocations, and arthritis. This page collects what Don Buford, MD has written about each of them: office based orthobiologic injections, the research this practice has run and presented, and arthroscopic surgery when surgery is the right answer. It is written for patients deciding what to do next and for physicians deciding what to refer.

Most shoulder pain starts in the rotator cuff

Rotator cuff pain is why people cannot sleep on one side, cannot reach a shelf, and cannot get through a workday. For many the disability is significant enough that they are unable to sleep or work for any length of time.

The first question is not which treatment you want. It is what is actually torn or irritated, and how much of it. A tendinopathy with no tear, a small partial thickness tear, a bursitis, and a large full thickness tear behave differently and respond to different things. Examination and imaging separate most of them, and when the picture is still unclear a needle scope under local anesthesia can settle it in the office.

What PRP and bone marrow concentrate can do for a cuff tear, and what they cannot

For partial tears and cuff tendon pain the injection evidence is real. A level 1 study in the journal Arthroscopy compared platelet rich plasma with a steroid injection for partial thickness rotator cuff tears. At 3 months the PRP patients had significantly better function and pain relief than the steroid patients, and that held even at the lower of the PRP doses tested. In this office a single injection is enough about 95 percent of the time, placed under ultrasound guidance.

Bone marrow concentrate has been studied here directly. In a practice study presented at the 2021 ARMI Spring Conference, patients with shoulder pain from rotator cuff tears received a single in office bone marrow concentrate injection. Two years later they reported 80 percent less pain and rated themselves 84 percent better by SANE score. A separate 25 patient office study followed partial thickness tears for a full year after a single bone marrow derived injection.

The limits matter as much as the results. PRP does not replace surgery for a type 2 SLAP lesion, a tear and detachment inside the joint. There the honest goal of an injection is a period of pain relief, and registry data sets expectations for how long that tends to last. Regenerative medicine keeps growing inside orthopedics and still cannot replace surgery for many conditions.

Dose is why studies on PRP disagree

Published trials of PRP in the rotator cuff reach opposite conclusions, largely because many of them never define the treatment they gave. A rotator cuff meta analysis in Arthroscopy defined PRP dose by volume alone. Dose is volume multiplied by platelet concentration, so two studies injecting the same number of milliliters can be giving very different treatments, and pooling them produces a conclusion that means little. When you read that PRP did or did not work for cuff tears, check first whether anyone reported the platelet count.

When repair surgery is the right answer

Since 2009 arthroscopic rotator cuff repair has healed about 90 percent of the tears it is used for, and recent studies report a 91 percent success rate when the repair is augmented biologically. Healing is something you can see: an arthroscopic video taken 2 years after repair of a 2 cm complete tear shows the tendon healed, with the sutures covered over by tendon and bursal tissue.

Biologic augmentation is now part of the operation. Adding PRP to a rotator cuff repair has been reported to lower retear rates. A scaffold patch used for cuff augmentation was tested straight out of the operating room and held 89 percent of its weight in PRP before being sutured into place. An intra-osseous injection into the greater tuberosity immediately after a repair takes under 3 seconds through an ordinary 18 gauge needle.

Age by itself is not a reason to rule out an operation. A published review compared rotator cuff repair in 54 patients over age 75 with 54 patients under 75 at 2 years, and age alone was not a barrier.

Frozen shoulder runs on a different clock

A frozen shoulder is a shoulder that has lost normal motion, and it is usually painful, especially at the end of whatever motion remains. It most often follows minor shoulder trauma. Patients are commonly told to wait it out and that it will settle in 1 to 2 years. The goal in this practice is closer to three months from the first evaluation.

Treatment depends on how much motion is gone and how much pain there is. For a patient who has already lost 50 percent or more of motion in any plane, an early manipulation under anesthesia, a procedure of about 10 to 15 minutes, has in Dr. Buford's experience restored motion the fastest and saved months of recovery.

Shoulder treatment at Texas Orthobiologics

Start here: what is causing your shoulder pain

Plain explanations of the common sources of shoulder pain and the range of options, from therapy through orthobiologics to surgery.

Office injections for rotator cuff tears and tendon pain

How PRP and bone marrow concentrate are used in the office for cuff tears, impingement and bursitis, including the level 1 comparison against a steroid injection and a patient result at 2 months.

Our bone marrow concentrate research in rotator cuff tears

The office study of a single bone marrow concentrate injection for partial thickness cuff tears, from procedure video through the 2 year outcome data presented at a national meeting.

Rotator cuff repair surgery: success rates and tendon healing

What modern arthroscopic repair actually achieves, what a healed tendon looks like 2 years later, and whether age changes the answer.

Adding biologics to a rotator cuff repair

The surgical side of orthobiologics: retear rates, scaffold patches loaded with PRP, intra-osseous injection technique, and a hard look at where the published evidence is weaker than it sounds.

Frozen shoulder and lost motion

What a frozen shoulder is, why the usual advice to wait it out costs you months, and when a manipulation under anesthesia is the fastest way back to normal motion.

SLAP tears, instability, and looking inside the shoulder

Where injections stop and arthroscopy starts, including SLAP lesions, chronic dislocations, and in office needle arthroscopy under local anesthesia.

Common questions

Does a rotator cuff tendon really heal after repair surgery?
Yes, and it can be seen directly. An arthroscopic video taken 2 years after repair of a 2 cm complete tear shows the tendon healed, with the sutures covered over by tendon and bursal tissue. Since 2009 arthroscopic rotator cuff repair has healed about 90 percent of the tears it is used for, and recent studies report a 91 percent success rate when the repair is augmented biologically.
Can PRP or bone marrow concentrate treat a rotator cuff tear without surgery?
For partial thickness tears and cuff tendon pain there is supporting evidence. A level 1 study in Arthroscopy found better function and pain relief at 3 months with a PRP injection than with a steroid injection for partial thickness tears. In a practice study of a single in office bone marrow concentrate injection for rotator cuff tears, patients reported 80 percent less pain and rated themselves 84 percent better by SANE score at 2 years. Results vary by patient and by the size and pattern of the tear, and some tears still need repair.
Will a PRP injection fix a SLAP tear?
No. PRP does not replace the need for surgery for a type 2 SLAP lesion, which is a tear and detachment of an intra-articular tendon attachment. The realistic goal of an injection there is a period of pain relief, and registry data is used to set expectations for how long that relief tends to last.
How long does a frozen shoulder take to get better?
Many patients are told it will resolve on its own over 1 to 2 years. The goal in this practice is closer to three months from the first evaluation. For a shoulder that has already lost 50 percent or more of its motion in any plane, an early manipulation under anesthesia, which takes about 10 to 15 minutes, has restored motion the fastest and saved many months of recovery.
Does adding PRP to a rotator cuff repair actually help?
The evidence is mixed and has to be read carefully. Adding PRP to a repair has been reported to reduce retear rates, but a meta analysis in Arthroscopy that found no benefit defined PRP dose by volume alone. Dose is volume multiplied by platelet concentration, so studies that report only milliliters are not comparing the same treatment, which is a major reason published conclusions conflict.
Am I too old for rotator cuff surgery or an orthobiologic procedure?
Age alone is not a barrier. A published review compared rotator cuff repair in 54 patients over age 75 with 54 patients under 75 at 2 year follow up and found that older patients still did well. The decision depends on the tear, the tissue quality and your goals rather than on a birth date.

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Texas Orthobiologics
Don Buford, MD

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Dallas, TX 75204

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