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Don Buford, MD, Orthopedic Surgeon / Regenerative Medicine Expert. Dallas, Texas / Blog » regenerative medicine
  • Have You Heard About Using Exosomes For Knee Arthritis?

    Have You Heard About Using Exosomes For Knee Arthritis?

    Posted in: Exosomes! |Tags: regenerative medicine |Posted on: 11-Nov-2025 | No. of views: 83

    In 2024 a research group in Iran did a well designed and controlled trial comparing 5cc of placental derived exosomes with 5cc of normal saline. 29 Patients were followed for six months.....58 knees total. Patients got MRI scans before and after.

    The result? There was no difference between the exosome knee and the normal saline knee in any measurable significant way.

    More work to be done on this topic for sure.....at the very least so far no clinical science supports using these allograft derived exosomes in knee arthritis.

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  • What Does A World Class PRP and Stem Cell and Orthopedic Surgery Clinic Look Like?

    What Does A World Class PRP and Stem Cell and Orthopedic Surgery Clinic Look Like?

    Tags: regenerative medicine |Posted on: 08-Nov-2025 | No. of views: 69

    Texas Orthobiologics is your PRP (platelet rich plasma) expert and your stem cell (bone marrow concentrate) expert AND your orthopedic surgery expert all in one Dallas location! Don Buford, MD, as the clinic's founder and Director, is involved in the care of every patient directly and his 26+ years as a clinical researcher and orthopedic surgeon means he has broad experience in orthopedic regenerative medicine.  As the two time President of the Interventional Orthobiologics Foundation and the recipient of the 2025 Lifetime Achievement Award from TOBI, Dr. Buford is widely recognized as one of the "go-to" experts in this rapidly growing field.

    We serve local patients in Dallas, Highland Park, University Park, Preston Hollow, Mesquite, Rockwall, Heath, Flower Mound, Plano, McKinney, Allen, Southlake, Westlake, Irving, Grapevine, Fort Worth, Richardson, Farmer's Branch, Colleyville.

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  • Don Buford / Texas Orthobiologics

    Don Buford / Texas Orthobiologics' Regenerative Medicine Research Is Growing!

    Posted in: Research |Tags: regenerative medicine |Posted on: 05-Oct-2025 | No. of views: 426

    Every 6 months or so I like to update my list of publications which include articles, book chapters, letters to the editor, and other references.  My first co-authored paper, "The Buford Complex..." was published way back in 1994!  So far in 2025, I have 4 articles/letters that have been published so far.

    I stay current with the latest orthopedic and regenerative medicine research because I want my patients to have access to the best results as documented in research from around the world.  Whenever I get a chance, I like to contribute and participate to this rapidly growing field within orthopedics.

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  • Can You Inject Fat Into A Knee To Make Arthritis Symptoms Better For A Year? Yes!

    Can You Inject Fat Into A Knee To Make Arthritis Symptoms Better For A Year? Yes!

    Posted in: Adipose Injections |Tags: regenerative medicine |Posted on: 30-Sep-2024 | No. of views: 783

    *MFAT (microfat) injection for knee osteoarthritis? Yes....the clinical evidence is only growing!*

    The best part?  This is a way to use adipose tissue in the USA that is compliant with the FDA regulations.
    This RCT published 9/5/2024 in Arthroscopy divided knee osteoarthritis patients into a MFAT group, a steroid group, and a normal saline group.

    75 patients total followed for one year. The MFAT group was significantly better than the other groups at every time point and out to one year.

    The steroid group had max benefit at 2 weeks which quickly returned to baseline.

    The two most prominent companies with adipose solutions in the USA right now are Lipogems and JointTechLabs.

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