A recently published level 1 study from Iranian authors concluded that their adipose based injection into arthritic knees led to some measurable cartilage regrowth in a few areas! In addition, the group treated with cultured allograft adipose MSCs (100 million cell dose) had less knee pain and better knee function at 1 year!
Although we cannot use cultured stem cells in the USA currently, studies like this one suggest that the future of orthobiologics as a disease modifying (ie. restoring cartilage) therapy lies in much higher cell dosing than we can do in the same day procedures. With our same day procedures, most of our success is with symptom modifying (ie. decreasing pain).
Click here for the open source article link: ARTICLE LINK
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