This video features a 1-month follow-up shared by Dr. Don Buford at Texas Orthobiologics, answering a frequent patient concern: How fast does Platelet-Rich Plasma (PRP) take to show results for knee pain?
Key Highlights:
- The Treatment: The patient received a targeted PRP injection in his right knee to treat localized pain and swelling.
- Timeline of Relief:
- Week 1: The patient experienced an almost immediate and significant reduction in joint swelling within the first week.
- Week 2: Around the two-week mark, he began noticing clear functional improvements, specifically noticing that his strength was starting to return.
- Results at 1 Month: At one month post-injection, the patient reports that the strength in his treated right leg has equalized and feels about the same as his healthy left leg.
- Overall Outcome: The patient rates his knee as 80% better compared to how it felt before the injection (referred to clinically by Dr. Buford as a Single Assessment Numeric Evaluation, or SANE score). Dr. Buford notes that these results are expected to continue improving, with the ultimate clinical goal of providing a year and a half or more of long-term relief.

